The effect of sweet almond on chronic renal failure

Evaluation of the effect of sweet almond capsule on function of kidney and quality of life in patients with chronic renal failure

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200516047465N1

Enrollment

Registered

2020-08-09

Start date

2020-08-05

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Chronic kidney disease, stage 2. Condition 2: Chronic kidney disease, stage 3. Chronic kidney disease, stage 2 Chronic kidney disease, stage 3

Interventions

Intervention 1: The drug is made in faculty of pharmacy, Shahid Beheshti University of Medical Sciences. Intervention group will receive capsules, containing 350 mg of almond, twice a day

30minutes before breakfast and 30 minutes before dinner. Both groups are treated for 8 weeks. Intervention 2: The placebo is made in faculty of pharmacy, Shahid Beheshti University of Medical Sciences

30minutes before breakfast and 30 minutes before dinner. Both groups are treated for 8 weeks.

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients with chronic kidney disease stage 2 and 3 Age range 18 to 75 years

Exclusion criteria

Exclusion criteria: Clinically unstable Malignancy Heart Failure Previous diagnosis of primary hyperoxaluria History of calcium oxalate kidney stone Known allergy to almond Liver failure Pregnancy Inability to communicate Polycystic kidney disease Acute infectious disease

Design outcomes

Primary

Measure	Time frame
Glomerular filtration rate. Timepoint: Before and after the intervention. Method of measurement: Modification of Diet in Renal Disease (MDRD) formula.	—

Secondary

Measure	Time frame
Serum creatinine. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Blood Urea Nitrogen. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;24-hour urine protein. Timepoint: before and after the intervention. Method of measurement: 24-hour urine evaluation.;Serum Albumin. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Serum uric acid. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Serum potassium. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Blood pressure. Timepoint: before and after the intervention. Method of measurement: Sphygmomanometer.;Hemoglobin. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Serum C-Reactive Protein (CRP). Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Lipid profile. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Fasting blood sugar. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Quality of Life. Timepoint: before and after the intervention. Method of measurement: The Short Form (36) Health Survey (SF-36).	—

Measure

Time frame

Serum creatinine. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Blood Urea Nitrogen. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;24-hour urine protein. Timepoint: before and after the intervention. Method of measurement: 24-hour urine evaluation.;Serum Albumin. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Serum uric acid. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Serum potassium. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Blood pressure. Timepoint: before and after the intervention. Method of measurement: Sphygmomanometer.;Hemoglobin. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Serum C-Reactive Protein (CRP). Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Lipid profile. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Fasting blood sugar. Timepoint: before and after the intervention. Method of measurement: Laboratory blood test.;Quality of Life. Timepoint: before and after the intervention. Method of measurement: The Short Form (36) Health Survey (SF-36).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSedighe Meghdadi

Mazandaran University of Medical Sciences

sedighe.meghdadi@yahoo.com+98 11 3325 5545

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026