The effect of Chelidonium majus and hyoscyamus niger with propolis on cutaneous Leishmaniasis

The effect of topical cream containing processes of Chelidonium majus and hyoscyamus niger with propolis on leishmaniasis : Randomized and double-blind clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200516047462N5

Enrollment

150

Registered

2022-04-12

Start date

2022-04-21

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cutaneous leishmaniasis. Cutaneous leishmaniasis

Interventions

Intervention 1: Intervention group: The intervention group includes 75 patients with cutaneous leishmaniasis. Topical cream containing 0.5 grams of Chelidonium majus and 0.5 gr of Hyoscyamus niger alo

Eligibility

Sex/Gender

All

Age

12 Years to 85 Years

Inclusion criteria

Inclusion criteria: Patients aged at least 12 years of both sexes Positive leishmania smear Real time PCR

Exclusion criteria

Exclusion criteria: Pregnancy and breastfeeding The number of lesions more than 10

Design outcomes

Primary

Measure	Time frame
Complete healing of the lesion. Timepoint: On arrival or day zero, 2, 4, 7, 14 and 21 days after treatment. Method of measurement: Based on measuring the diameter of the induration of the lesion using a caliper.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMorteza Kosari

Kashan University of Medical Sciences

kosarimorteza12@gmail.com+98 31 5554 2999

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026