Effect of Chelidonium majus and hyoscyamus niger with propolis on psoriasis

Evaluation of the effect of topical cream containing processes of Chelidonium majus and hyoscyamus niger with propolis on psoriasis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200516047462N4

Enrollment

Registered

2022-01-15

Start date

2022-01-15

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis. Psoriasis

Interventions

Intervention 1: Intervention group: The intervention group is included 44 patients with psoriasis. During three weeks, topical cream containing 0.5 grams of Chelidonium majus and 0.5 grams of Hyoscya

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: known case of psoriasis Clinical judgment of the specialist physician based on receiving the product Patients with psoriasis during 3 months, and are in the age range of 18 to 85 years

Exclusion criteria

Exclusion criteria: Existence of any history of allergy to any herbal product pregnancy for females

Design outcomes

Primary

Measure	Time frame
PASI Score. Timepoint: At the beginning of the study, 4, 7, 14, 28 and 40 days after treatment. Method of measurement: Evaluated quantitatively and qualitatively of wounds extent and redness of the skin and the extent of involvement of different parts of the body and itching .;Expression of TNF-a, IL-17 gene. Timepoint: After 40 days. Method of measurement: Real Time PCR.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMorteza Kosari

Kashan University of Medical Sciences

kosarimorteza12@gmail.com+98 31 5554 2999

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026