Diabetic food ulcers. Ulcer of lower limb, not elsewhere classified
Conditions
Interventions
Intervention 1: The intervention group is included 44 patients with diabetic foot ulcers. During three weeks, topical cream containing 0.5 grams of Chelidonium majus and 0.5 grams of Hyoscyamus niger
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Patients with diabetes who take insulin and have diabetic foot ulcers and are in the age range of 18 to 85 years. Clinical judgment of the specialist physician based on receiving the product The patient's ability and its personal desire to fill out of personal consent form to enter the study
Exclusion criteria
Exclusion criteria: Existence of any history of allergy to any herbal product Patients who need surgery for their wounds
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Size and extent of wound. Timepoint: At the beginning of the study, 4 days after treatment and 7 days after treatment, 14 days after treatment, 21 days after treatment. Method of measurement: In millimeters.;The infiltration of inflammatory cells, neutrophils, monocytes, synthesis and maturation of collagen, fibroblasts and keratinocytes and induction of angiogenesis. Timepoint: 21 days after treatment. Method of measurement: Tissue sample.;Nuclear hypertrophy of endothelial cells, vacuoles, diabetic foot ulcer granulation and tissue fibrosis. Timepoint: Twenty one days after treatment. Method of measurement: Histology.;The duration of treatment, the speed of recovery, the rate of symptoms reduction and the duration of disease recurrence. Timepoint: Twenty one days after treatment. Method of measurement: Check list. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMorteza Kosari
Kashan University of Medical Sciences
Outcome results
None listed