Chronic kidney disease. Chronic kidney disease (CKD)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients who were a candidate for the second time embedding of permanent arteriovenous catheters Informed consent to participate in the study Age above 18 years old
Exclusion criteria
Exclusion criteria: History of major hemorrhages (requiring blood transfusion, retroperitoneal or intracranial hemorrhage, inducing hypovolemia, leading to more than two units decrease in hemoglobin) within the previous three months Progressive diabetic retinopathy Less than 12 months of life-expectancy because of systemic disease or malignancies Poorly controlled hypertension (systolic blood pressure>200 mmHg or diastolic blood pressure>100 mmHg measured three times within two weeks) Absolute platelet count less than 100000 International normalized ratio (INR)=1.3 Partial thrombin time (PTT)= 5 folds than the normal range Hypersensitivity to Warfarin Active peptic ulcer Pregnancy or lactation Documented aortic aneurysm
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Permcath function. Timepoint: In every hemodialysis session. Method of measurement: Catheter clotting defined as the gross visible occlusion of the catheter or the dialysis performance with less than 250 ml per minute velocity. | — |
Countries
Iran (Islamic Republic of)
Contacts
Esfahan University of Medical Sciences