Radiation induced skin reactions. A radiation burn is damage to the skin or other biological tissue caused by exposure to radiation. The radiation types of greatest concern are thermal radiation, radio frequency energy, ultraviolet light and ionizing radiation.
Conditions
Interventions
Intervention 1: Intervention group: nano-curcumin Capsule (Exir Nano Sina Co.) as an 80mg gelatin capsule, one capsule per day after breakfast, from the first radiotherapy fraction to the last radiati
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Breast cancer patients who will undergo radiotherapy.
Exclusion criteria
Exclusion criteria: Patients whose breast region have previously been irradiated. Patients with bilateral breast cancer. Patients receiving concurrent chemotherapy and radiotherapy Patients taking anticoagulants such as warfarin (Coumadin) or heparin Patients with skin conditions (such as bleeding, ulcers or incurable wounds) or sensitivity to formulations Patients treated by anti-epidermal growth factor (EGRF) Patients undergoing minor radiation to the breast area Patients with special skin allergies Patients with diagnosis of inflammatory breast cancer and reconstructive treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin burn grade. Timepoint: Determination of skin reaction? at the beginning of the study (before the intervention), 7, 14, 21, 28 and 35 days after the start of nano-curcumin capsule consumption. Method of measurement: Determination of skin reaction (skin burn grade) according to the criteria of the Radiotherapy-Oncology group by a radiation oncologist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactTamara Talakesh
Kashan University of Medical Sciences
Outcome results
None listed