Skip to content

The prophylactic effect of oral hydroxy-chloroquine in close contacts of COVID-19 patients

The prophylactic effect of oral hydroxy-chloroquine in close contacts of COVID-19 patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200513047426N1
Enrollment
500
Registered
2020-06-27
Start date
2020-06-21
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid19. Coronavirus infection, unspecified

Interventions

Intervention 1: Intervention group: Cases of this group are treated with preventive treatment of hydroxychloroquine as follows.1-hydroxychloroquine 400 mg tablet once on the first night at 22:002- hy

Sponsors

Boushehr University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Close contact with a person with COVID-19 who has been diagnosed positive with a definitive test. Close contact: contact, hand shake and talking at least once in the last 2 days for less than 2 meters with COVID-19 patient who have been diagnosed positive with a definitive test. Family, friends, relatives who have been in the same place for a period of 4 hours or more in the last 2 days with a COVID-19 patient who have been diagnosed with a definitive test . Medical staff, including physicians, nurses, midwives, and service personnel which have been in contact with COVID-19 patient who has been diagnosed with a definitive test in the past three days.

Exclusion criteria

Exclusion criteria: Lack of satisfaction from entered persons The presence of diseases or conditions in which the use of hydroxychloroquine is as a contraindication, such as patients with heart failure who take QT prolonging drugs are as contraindications. Existence of distorting factors during the implementation of clinical trial.+ During the study, people should be in home quarantine . + Do not Excessive use of vitamins and medications.+ has Meals like family’s.+has Regular sleep cycle Complications of hydroxychloroquine based on the Iranian rheumatology association include the following:1- Nausea, decreased appetite and diarrhea 2- Skin allergies 3- Skin discoloration 4- Ocular sensitivity 5- Headache 6- Rush

Design outcomes

Primary

MeasureTime frame
Percentage of people who have not been diagnosed with Covid19 after co-administration of hydroxychloroquine. Timepoint: The end of study. Method of measurement: Diagnostic COVID-19 Kits.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRamin Rezaee

Boushehr University of Medical Sciences

Drrezaee.ramin@yahoo.com+98 77 3345 2227

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026