The effects of Dexmedetomidine and Midazolam on hemodynamic responses after tracheal intubation in elderly patients under Cataract surgery with general anesthesia in comparison to control group

The effects of Dexmedetomidine and Midazolam on hemodynamic responses after tracheal intubation in elderly patients under Cataract surgery with general anesthesia in comparison to control group in Isfahan Feyz hospital from 2018-2019

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200510047389N2

Enrollment

210

Registered

2020-05-19

Start date

2020-05-21

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Cataract surgery. Condition 2: Tracheal intubation. Cataract in diseases classified elsewhere Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

Interventions

Intervention 1: Intervention group A: Initially, personal consent is obtained from the patients. Then the patient is placed on the operating bed and vital signs were recorded by standard monitoring de

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: Elderly patients over 65 years old candidate for cataract surgery with general anesthesia ASA2-3 No allergy to any of the study medications

Exclusion criteria

Exclusion criteria: Hemodynamic changes over 30% that needed intervention Patient who refusing Severe drug complications History of using opioid and alcohol Changing the method of anesthesia Severe chronic disease

Design outcomes

Primary

Measure	Time frame
Systolic Blood pressure. Timepoint: Before the anesthesia, 1, 3, 5, 10 during anesthesia, entering the recovery and discharge time. Method of measurement: Blood pressure monitoring device.;Diastolic blood pressure. Timepoint: Before the anesthesia, 1, 3, 5, 10 during anesthesia, entering the recovery and discharge time. Method of measurement: Blood pressure monitoring device.;Mean arterial Blood pressure. Timepoint: Before the anesthesia, 1, 3, 5, 10 during anesthesia, entering the recovery and discharge time. Method of measurement: Blood pressure monitoring device.;Heart rate. Timepoint: Before the anesthesia, 1, 3, 5, 10 during anesthesia, entering the recovery and discharge time. Method of measurement: Monitoring device.;Arterial oxygen saturation percentage. Timepoint: Before the anesthesia, 1, 3, 5, 10 during anesthesia, entering the recovery and discharge time. Method of measurement: Pulse oximetry.	—

Measure

Time frame

Systolic Blood pressure. Timepoint: Before the anesthesia, 1, 3, 5, 10 during anesthesia, entering the recovery and discharge time. Method of measurement: Blood pressure monitoring device.;Diastolic blood pressure. Timepoint: Before the anesthesia, 1, 3, 5, 10 during anesthesia, entering the recovery and discharge time. Method of measurement: Blood pressure monitoring device.;Mean arterial Blood pressure. Timepoint: Before the anesthesia, 1, 3, 5, 10 during anesthesia, entering the recovery and discharge time. Method of measurement: Blood pressure monitoring device.;Heart rate. Timepoint: Before the anesthesia, 1, 3, 5, 10 during anesthesia, entering the recovery and discharge time. Method of measurement: Monitoring device.;Arterial oxygen saturation percentage. Timepoint: Before the anesthesia, 1, 3, 5, 10 during anesthesia, entering the recovery and discharge time. Method of measurement: Pulse oximetry.

—

Secondary

Measure	Time frame
Surgery complictions. Timepoint: After the surgery in recovery. Method of measurement: Physical examination and observation by physician.;Recovery time. Timepoint: After the surgery. Method of measurement: Minute.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Beidokhti

Esfahan University of Medical Sciences

Amir.beidokhti71@gmail.com+98 31 3260 3538

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026