Evaluation of the clinical effects of nanohydroxy apatite toothpaste during home bleaching treatment

Evaluation of Effect of toothpaste containing nanohydroxyapatite particles on dental sensitivity , color change and Gingival Index during home bleaching treatment

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200509047374N1

Enrollment

Registered

2020-05-17

Start date

2020-06-21

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth sensitivity after bleaching. Persons encountering health services for specific procedures and health care

Interventions

Intervention 1: Control group: Do prophylaxis with oil-free prophylactic paste, to remove foreign pigments one week before bleaching treatment, teaching how to brush and floss correctly (brush 3 times

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Having natural front teeth with colors A2, B2, C2, D2 and darker (Vitapan Classic Shade) Have at least 24 teeth Lack of any kind of frontal restoration Proper oral hygiene People without caries in the front teeth Lack of Gingivitis and Periodontal Diseases No dental root exposure Lack of NCCL (Non Caries Cervical Lesions) Lack of ortho treatment Patients without a history of dental sensitivity to cold and heat or expressing allergies with airborne powder tests Do not use any anti-sensitivity compounds for the past three months No pregnancy or lactation Lack of Calculus People without a history of bleaching treatment in the past No smoking People without florosis and tetracycline

Exclusion criteria

Exclusion criteria: Lack of willingness of the participant to continue treatment Severe sensitivity due to bleaching treatment

Design outcomes

Primary

Measure	Time frame
The severity of tooth sensitivity. Timepoint: Days 1, 3, 7, 10 and 14 after the start of bleaching. Method of measurement: based on the VAS (Visual Analog Scale)test.;The rate of tooth discoloration. Timepoint: Days 1, 3, 7, 10 and 14 after the start of bleaching. Method of measurement: Chromaticity (color intensity) with Easy shade device.;Gingival index. Timepoint: Days 1, 3, 7, 10 and 14 after the start of bleaching. Method of measurement: During a clinical examination with a probe and observing the condition of the gums.	—

Measure

Time frame

The severity of tooth sensitivity. Timepoint: Days 1, 3, 7, 10 and 14 after the start of bleaching. Method of measurement: based on the VAS (Visual Analog Scale)test.;The rate of tooth discoloration. Timepoint: Days 1, 3, 7, 10 and 14 after the start of bleaching. Method of measurement: Chromaticity (color intensity) with Easy shade device.;Gingival index. Timepoint: Days 1, 3, 7, 10 and 14 after the start of bleaching. Method of measurement: During a clinical examination with a probe and observing the condition of the gums.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFaeze Elahi Chatrudi

Zahedan University of Medical Sciences

Nikadp.94@gmail.com+98 54 3341 4004

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026