The relationship between combined exercise (strength and endurance) and inflammation in obese elderly. Senility
Conditions
Interventions
Intervention 1: Intervention group: This group lasts for 16 weeks, with three sessions per week and each session is 90 minutes. Aerobic and resistance exercises were held in the morning (6 to 7:30). T
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
Male
Age
60 Years to 70 Years
Inclusion criteria
Inclusion criteria: Being between 60 and 70 years old No history of orthopedic diseases in the last 5 years, vision problems Not having daily sports activities for at least two years Stable body weight (±5 kg) for at least six months. The ability to perform sports intervention (exercise capacity Eating an omnivorous diet
Exclusion criteria
Exclusion criteria: People who do not have the ability to implement the training protocol and tests, (suspicious cases) diagnosis of cardiovascular disease (angina, myocardial infarction, stroke, peripheral artery occlusion disease, heart failure, cardiac arrhythmia), Type 1 and 2 diabetes. Absence of kidney failure and liver disease, coagulation disorders, chronic gastrointestinal disorders (e.g. Crohn's disease), pancreatic insufficiency, immunological disease (e.g. autoimmune disease).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete blood cell count or CBC and white blood cell counts. Timepoint: Before 16 weeks of training and after 16 weeks of training, it is taken from the experimental and control groups. Method of measurement: Using a blood sample.;Nuclear factor kappa light chain enhancer of activated B lymphocytes (NF-KB). Timepoint: Before 16 weeks of training and after 16 weeks of training, it is taken from the experimental and control groups. Method of measurement: Using polymerase chain reaction (PCR).;Tumor Necrosis Factor-Alfa ,TNF-a. Timepoint: Before 16 weeks of training and after 16 weeks of training, it is taken from the experimental and control groups. Method of measurement: Using polymerase chain reaction (PCR).;Determination of miR-145 levels. Timepoint: Before 16 weeks of training and after 16 weeks of training, it is taken from the experimental and control groups. Method of measurement: Using polymerase chain reaction (PCR).;Determining miR-130b levels. Timepoint: Before 16 weeks of training and after 16 weeks of training, it is taken from the experimental and control groups. Method of measurement: Using polymerase chain reaction (PCR).;Eotaxin 1. Timepoint: Before 16 weeks of training and after 16 weeks of training, it is taken from the experimental and control groups. Method of measurement: Using polymerase chain reaction (PCR).;Adiponectin. Timepoint: Before 16 weeks of training and after 16 weeks of training, it is taken from the experimental and control groups. Method of measurement: Using polymerase chain reaction (PCR).;Vascular endothelial growth factor (VEGF). Timepoint: Before 16 weeks of training and after 16 weeks of training, it is taken from the experimental and control groups. Method of measurement: Using polymerase chain reaction (PCR).;?????????? 10 (IL-10). Timepoint: Before 16 weeks of training and after 16 weeks of training, it is taken from the experimental and control groups. Method of measurement: Serum level using ELISA kit.;Cognitive functio | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure variables. Timepoint: Before and after completing 16 weeks of training. Method of measurement: Resting and post-exercise values using measurements of systolic blood pressure, diastolic blood pressure and heart rate.;Body composition and weight. Timepoint: Before and after completing 16 weeks of training. Method of measurement: Using measurements of weight, body mass index (BMI), fat percentage, lean mass and waist circumference.;Physical fitness. Timepoint: Before and after completing 16 weeks of training. Method of measurement: By measuring the strength of the upper and lower limbs by means of a dynamometer and maximum oxygen consumption (VO2max). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMina Safari
Islamic Azad University
Outcome results
None listed