The efficacy of plasmapheresis in the treatment of patients poisoned with aluminum phosphide

Evaluation of the efficacy of plasmapheresis in comparison with conventional treatment on electrolyte and coagulation parameters in patients poisoned with aluminum phosphide

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200507047344N2

Enrollment

Registered

2020-12-05

Start date

2020-11-21

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aluminum phosphide poisoning. Toxic effect of pesticides

Interventions

Intervention 1: Control group: Patients in this group will receive only routine treatment. Continuous injection of normal saline and dopamine will be done along with olive oil gavage. In addition, int

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Aged between 20 and 65 years Poisoned with aluminum phosphide Patient/attendant consent to participate in the study

Exclusion criteria

Exclusion criteria: Any risk of coagulation disorders History of chronic kidney failure

Design outcomes

Primary

Measure	Time frame
Systolic blood pressure. Timepoint: Immediately upon arrival at the hospital and every hour to 6 hours after the intervention. Method of measurement: Sphygmomanometer.;?Diastolic blood pressure. Timepoint: Immediately upon arrival at the hospital and every hour to 6 hours after the intervention. Method of measurement: Sphygmomanometer.;Creatinine. Timepoint: Immediately upon arrival at the hospital and 12 hours after the intervention. Method of measurement: Blood test.;Sodium. Timepoint: Immediately upon arrival at the hospital and 12 hours after the intervention. Method of measurement: Blood test.;Magnesium. Timepoint: Immediately upon arrival at the hospital and 12 hours after the intervention. Method of measurement: Blood test.;Platelets. Timepoint: Immediately upon arrival at the hospital and 12 hours after the intervention. Method of measurement: Blood test.	—

Measure

Time frame

Systolic blood pressure. Timepoint: Immediately upon arrival at the hospital and every hour to 6 hours after the intervention. Method of measurement: Sphygmomanometer.;?Diastolic blood pressure. Timepoint: Immediately upon arrival at the hospital and every hour to 6 hours after the intervention. Method of measurement: Sphygmomanometer.;Creatinine. Timepoint: Immediately upon arrival at the hospital and 12 hours after the intervention. Method of measurement: Blood test.;Sodium. Timepoint: Immediately upon arrival at the hospital and 12 hours after the intervention. Method of measurement: Blood test.;Magnesium. Timepoint: Immediately upon arrival at the hospital and 12 hours after the intervention. Method of measurement: Blood test.;Platelets. Timepoint: Immediately upon arrival at the hospital and 12 hours after the intervention. Method of measurement: Blood test.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShafeajafar Zoofaghari

Esfahan University of Medical Sciences

shafeajafar@med.mui.ac.ir+98 31 3268 7610

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026