COVID-19 disease. COVID-19, virus not identified
Conditions
Interventions
Intervention 1: Intervention group: The standard treatment regimen for COVID-19 based on the Ministry of Health's protocol, including hydroxychloroquine sulfate (Amin Pharmaceutical company, Isfahan)
Sponsors
Bandare-abbas University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age =18 years Positive polymerase chain reaction (PCR) test for COVID-19 or/and lung involvement in imaging Primary clinical symptoms Hospitalized Signing informed consent and willingness of study participant to accept randomization to any assigned treatment arm
Exclusion criteria
Exclusion criteria: Underlying diseases (heart disease, chronic hypertension, severe renal failure, severe liver failure, and thyroid disorders) Use of warfarin, SSRIs, MAOIs, diuretics, corticosteroids, and antiarrhythmic drugs History of drug allergy Pregnancy and breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body temperature. Timepoint: Before intervention and daily during the study. Method of measurement: Thermometer.;Respiratory rate. Timepoint: Before intervention and daily during the study. Method of measurement: Respiratory Count.;Oxygen saturation. Timepoint: Before intervention and daily during the study. Method of measurement: Pulse oximeter. | — |
Secondary
| Measure | Time frame |
|---|---|
| Lymphocytopenia. Timepoint: Before intervention and days 7 and 14 after the intervention. Method of measurement: Cell count.;C-reactive protein. Timepoint: Before intervention and days 7 and 14 after the intervention. Method of measurement: C-RP kit.;Incidence of serious adverse events. Timepoint: Before intervention and daily during the study. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Fathalipour
Bandare-abbas University of Medical Sciences
Outcome results
None listed