Comparing Lactobacillus plantarum 299v with Placebo in treating irritable bowel syndrome patients

A Double Blind Randomized Clinical Trail: Comparing Lactobacillus plantarum 299v with Placebo in treating irritable bowel syndrome patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200504047303N1

Enrollment

190

Registered

2020-05-16

Start date

2635-10-10

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

irritable bowel syndrome. Irritable bowel syndrome

Interventions

Intervention 1: Intervention group: Patients enrolled suffering from IBS were divided in two groups Group A received Lactobacillus plantarum 299v. Intervention 2: Control group: Patients enrolled suff

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Fulfilling the Rome III criteria for IBS Willing to participate Committed for follow up throughout the study period

Exclusion criteria

Exclusion criteria: History of major abdominal surgery, Organic intestinal disease or chronic infectious disease like HIV or tuberculosis Pregnant and the female breastfeeding their babies Anyone with current use of antibiotics

Design outcomes

Primary

Measure	Time frame
Symptomatic treatment with out Lactobacillus plantarum 299v. Timepoint: conducted for six (6) months. Method of measurement: Daily frequency of abdominal pain was considered as primary end point. The secondary end points were improvement in the severity of abdominal pain, severity of the bloating and feeling of partial rectal emptying. Both the primary and the secondary end points were gauged on the visual analogue scale from zero (0) to ten (10), 0 being normal and 10 being very severe. In each visit the patients were examined thoroughly and all the parameters were noted along with the medication compliance.	—

Measure

Time frame

Symptomatic treatment with out Lactobacillus plantarum 299v. Timepoint: conducted for six (6) months. Method of measurement: Daily frequency of abdominal pain was considered as primary end point. The secondary end points were improvement in the severity of abdominal pain, severity of the bloating and feeling of partial rectal emptying. Both the primary and the secondary end points were gauged on the visual analogue scale from zero (0) to ten (10), 0 being normal and 10 being very severe. In each visit the patients were examined thoroughly and all the parameters were noted along with the medication compliance.

—

Countries

Pakistan

Contacts

Public ContactDr Muhammad Kamran Hassan

Lady Reading Hospital, Peshawar

drkamran177@yahoo.com+92 91 9211430

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 13, 2026