The Effect of Oral Premedication with Novafen, Naproxen, and Ibuprofen on the Success of the Inferior Alveolar Nerve Block for Teeth with Symptomatic Irreversible Pulpitis

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200504047302N2

Enrollment

125

Registered

2020-06-10

Start date

2020-05-04

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulp disease. Other and unspecified diseases of pulp and periapical tissues

Interventions

Intervention 1: Intervention group: - Group 1: premedication with Ibuprofen 400 mg (Neda pharmaceutical company), 1 hour before treatment. Intervention 2: Intervention group: premedication with Novafe

Eligibility

Sex/Gender

All

Age

20 Years to 55 Years

Inclusion criteria

Inclusion criteria: Age 20 to 55 years acute irreversible pulpitis mandibular molar The ability of understanding the pain factors No medication in the past 8 hours

Exclusion criteria

Exclusion criteria: Severe apical periodontitis Sign or symptoms indicating pulp necrosis Systemic disease Pregnant or milking patient Allergic reactions to drugs

Design outcomes

Primary

Measure	Time frame
A Randomized Clinical Trial Comparing the Effect of Oral Premedication with Novafen, Naproxen, and Ibuprofen on the Success of the Inferior Alveolar Nerve Block for Teeth with Symptomatic Irreversible Pulpitis. Timepoint: 1 HOUR AFTER DRUG CONSUMPTION. Method of measurement: Heft Parker method of pain measurement.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Jafarzadeh

Mashhad University of Medical Sciences

hamid_j365@yahoo.com+98 51 3882 9501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026