The Effect of Oral Premedication with Novafen and Ibuprofen on the Response of the Patients with Acute Irreversible Pulpitis to the Cold, Heat, Electric, and Pulse Oximetry Tests

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200504047302N1

Enrollment

Registered

2020-06-08

Start date

2020-05-10

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulp disease. Other and unspecified diseases of pulp and periapical tissues

Interventions

Intervention 1: Intervention group:Use a 400 mg ibuprofen (Neda, Tehran, Iran) one hour before treatment. Intervention 2: Intervention group: Take one novafen (Alhavi, Isfahan, Iran) one hour before t

Eligibility

Sex/Gender

All

Age

20 Years to 55 Years

Inclusion criteria

Inclusion criteria: Age 20 to 55 years acute irreversible pulpitis single root/canal mandibular premolar The ability of understanding the pain factors Mature apex

Exclusion criteria

Exclusion criteria: Drug consumption in past 8 hours Severe apical periodontitis Clinical sign of necrosis Systemic disease

Design outcomes

Primary

Measure	Time frame
Pre-treatment effect on cold test result; pre-treatment effect on heat test; pre-treatment effect on electrical test result; pre-treatment effect on pulse oximetry test result. Timepoint: 1 HOUR AFTER DRUG CONSUMPTION. Method of measurement: test result as positive or negative.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Jafarzadeh

Mashhad University of Medical Sciences

hamid_j365@yahoo.com+98 51 3882 9501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026