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Comparison of the sedative effect of Remifentanil and Dexmidetomidine

Comparison of the sedative effect of Remifentanil and Dexmidetomidine in patients undergoing venous arterial fistula implantation

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200502047269N1
Enrollment
32
Registered
2020-11-26
Start date
2020-05-21
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing venous arterial fistula implantation.

Interventions

Intervention 1: Intervention group 1: Dexamidomethidine administration (bolus dose of 0.4 µg / kg intravenously over 10 minutes and maintenance dose of 0.5 to 1.00 µg / kg / min). Its manufacturer is

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age group 19 to 60 years Patients with stable hemodynamic status

Exclusion criteria

Exclusion criteria: Patients with a history of cardiovascular abnormalities Patients with a history of chronic diseases such as liver disease Patients with a history of allergies to anesthetics, including opioids Patients with a history of opium use Pregnant or lactating women Recent respiratory tract infection Severe bronchopulmonary disease

Design outcomes

Primary

MeasureTime frame
Pain score. Timepoint: At the moment after the operation and also every half an hour, up to two hours after the operation. Method of measurement: Use of Visual Analogue Scale (VAS) scoring system.

Secondary

MeasureTime frame
Nausea and vomiting. Timepoint: After surgery. Method of measurement: Observation.;Hypertension. Timepoint: After surgery. Method of measurement: Mercury barometer.;Oxygen saturation. Timepoint: After surgery. Method of measurement: Pulse oximetry.;Tachycardia and bradycardia. Timepoint: After surgery. Method of measurement: Monitoring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Maleki

Iran University of Medical Sciences

dr.alireza_maleki@irimed.org+98 21 2264 1112

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026