COVID-19. COVID-19
Conditions
Interventions
Intervention 1: Intervention group 1: hospitalized patients received convalescent plasma with 2-5 cc/kg transfused on 1, 3, 5 days after treatment that treated with the standard national guideline. In
Sponsors
Oroumia University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Positive PCR test The life-threatening disease is defined as respiratory failure dyspnea respiratory frequency = 30/min blood oxygen saturation = 93% partial pressure of arterial oxygen to fraction of inspired oxygen ratio 50% within 24 to 48 hours
Exclusion criteria
Exclusion criteria: Pregnancy Hypersensitivity to blood or blood products Uncontrolled bacterial infection Disagreement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hospitalization time. Timepoint: 0, 1, 3, 7, 14 days. Method of measurement: check list.;ICU admission time. Timepoint: 0, 1, 3, 7, 14 days. Method of measurement: check list.;Mechanical ventilation time. Timepoint: 0, 1, 3, 7, 14 days. Method of measurement: check list.;Survival rate. Timepoint: 0, 1, 3, 7, 14 days. Method of measurement: check list. | — |
Secondary
| Measure | Time frame |
|---|---|
| CT scan. Timepoint: 0- 1- 3- 7- 14 days. Method of measurement: CT scan.;Serological tests. Timepoint: 0- 1- 3- 7- 14 days. Method of measurement: ELISA.;Hematological markers. Timepoint: 0- 1- 3- 7- 14 days. Method of measurement: flowcytometry.;Clinical findings. Timepoint: 0- 1- 3- 7- 14 days. Method of measurement: check list. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRahim Asghari
Oroumia University of Medical Sciences
Outcome results
None listed