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Effect of Propofol Drug on Lipid Level and Blood PH

Examining the effect of using the drug propofol in anesthesia on the blood fat and bicarbonate ion levels in patients undergoing spinal surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200501047254N3
Enrollment
58
Registered
2024-03-02
Start date
2024-02-20
Completion date
Unknown
Last updated
2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spine surgery.

Interventions

Intervention group: This group will include patients who are candidates for spine surgery under anesthesia with propofol at a dose of 10 mg/kg/hour Product of B-Broun, Germany that they have been unde

Sponsors

Gonabad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Informed consent of the patient to participate in the research Patient age between 20 and 70 years Patient with ASA class I and II Duration of surgery at least 4 hours Blood fat before the operation should be at a normal level (less than 200). Blood pH should be at a normal level before the operation. Do not have underlying diseases including liver and blood diseases. The patient should not be a candidate for surgery due to trauma and in emergency conditions. The patient does not have a history of drug addiction. The patient should not be overweight or obese. The patient does not have a history of taking antipsychotic drugs

Exclusion criteria

Exclusion criteria: Patient withdrawal from participating in research Occurrence of heart and respiratory problems before the start of the plan

Design outcomes

Primary

MeasureTime frame
Blood triglyceride levels. Timepoint: Before starting NPO, 4 hours after surgery. Method of measurement: Triglyceride test product of Dialab company.

Secondary

MeasureTime frame
Blood PH level. Timepoint: Before starting fasting, 4 hours after surgery. Method of measurement: ABG Test.;Blood bicarbonate ion level. Timepoint: Before starting fasting, 4 hours after surgery. Method of measurement: ABG Test.;HDL Level. Timepoint: Before starting NPO, 4 hours after surgery. Method of measurement: HDL test product of Dialab company.;LDL Level. Timepoint: Before starting NPO, 4 hours after surgery. Method of measurement: LDL test product of Bionic company.;Cholesterol Level. Timepoint: Before starting NPO, 4 hours after surgery. Method of measurement: Cholesterol test product of Dialab company.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Taghi Khodadadi

Gonabad University of Medical Sciences

dr_khodadadi_m@yahoo.com+98 51 5723 6833

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026