Evaluation of the efficacy of Olanzapine and Aripiprazole in patients with psychotic disorders

A comparative study of the effectiveness and safety of Aripiprazole and Olanzapine in patients with psychotic disorders; A clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200430047250N1

Enrollment

Registered

2020-09-11

Start date

2020-07-18

Completion date

Unknown

Last updated

2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psychotic Disorders.

Interventions

Intervention group: This study is a double-blind clinical trial. The study population includes all patients with psychotic disorders who in 1398, referred to Farabi Hospital in Kermanshah for treatmen

Eligibility

Sex/Gender

All

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Diagnosing psychotic disorders through clinical interview and DSM-5 & ICSD-III criteria Prescribing Aripiprazole or Olanzapine as a treatment strategy for psychotic disorders Patients aged 18-64 years

Exclusion criteria

Exclusion criteria: Patients simultaneously taking medications such as sleeping pills and Aripiprazole or Olanzapine (drugs that have high sedative effects) Patients suffering dependence on or abuse of Aripiprazole or Olanzapine Patients with multiple chronic physical illnesses such as Diabetes, High Blood Pressure, and Rheumatism Patients with certain health conditions( preventing them form taking Aripiprazole or Olanzapine )

Design outcomes

Primary

Measure	Time frame
Measurement of body mass index in psychotic patients treated with olanzapine or aripiprazole. Timepoint: At the beginning of the study and one and two months after starting the drug. Method of measurement: Height and weight scales.;Efficacy of olanzapine and aripiprazole in psychotic patients. Timepoint: At the beginning of the study and one and two months after starting the drug. Method of measurement: PANSS Questionnaire.	—

Measure

Time frame

Measurement of body mass index in psychotic patients treated with olanzapine or aripiprazole. Timepoint: At the beginning of the study and one and two months after starting the drug. Method of measurement: Height and weight scales.;Efficacy of olanzapine and aripiprazole in psychotic patients. Timepoint: At the beginning of the study and one and two months after starting the drug. Method of measurement: PANSS Questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNima Gheitouly

Kermanshah University of Medical Sciences

nimagheitouly@yahoo.com+98 83 3428 3987

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026