Efficacy of umbilical cord Mesenchymal Stem Cells on patients with neuromuscular disorders

Assessment of Efficacy of umbilical cord derived mesenchymal Stem Cells transplantation on movement improvement in patients with neuromuscular disorders

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200426047213N1

Enrollment

120

Registered

2020-05-14

Start date

2019-10-23

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Dystrophinopathy(Duchenne muscular dystrophy, Becker muscular dystrophy). Condition 2: Spinal muscular atrophy. Condition 3: other Myopathy (Congenital myopathy, Congenital myasthenic syndrome). Condition 4: Charcot-Marie-Tooth). Muscular dystrophy Spinal muscular atrophy and related syndromes Congenital myopathies Hereditary motor and sensory neuropathy

Interventions

Intervention 1: Intervention group: In intervention group or test group the transplantation or injection of mesenchymal stem cell will be done. In this study the site of transplantation is in operatio

Eligibility

Sex/Gender

All

Age

4 Years to 35 Years

Inclusion criteria

Inclusion criteria: Genetic confirmed patients with Dystrophinopathy(Duchenne muscular dystrophy, Becker muscular dystrophy) Genetic confirmed patients with Neuropathy(Spinal muscular atrophy, Charcot-Marie-Tooth) Genetic confirmed patients with other Muscular dystrophy(Limb girdle muscular dystrophy, Congenital muscular dystrophy) Genetic confirmed patients with other Myopathy (Congenital myopathy, Congenital myasthenic syndrome)

Exclusion criteria

Exclusion criteria: Patients with cancer Patients with chromosomal defects Patients with HIV, HCV, HBV, HTLV1,2 Dissatisfaction for entering the study

Design outcomes

Primary

Measure	Time frame
Muscle power. Timepoint: Before study, 6 and 9 and 12 months after Mesenchymal stem cell transplantation. Method of measurement: Walking distance in 6 minutes and muscular force examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Kazem Bakhshandeh

Tehran Islamic Azad university of Medical Sciences

drbakhshandeh.com@gmail.com+98 21 2640 0779

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026