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Investigation of the effect of NAC on the treatment of acute respiratory distress syndrome in patients undergoing mechanical ventilation in the intensive care unit

Investigation of the effect of NAC on the treatment of acute respiratory distress syndrome in patients undergoing mechanical ventilation in the intensive care unit

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200425047201N1
Enrollment
60
Registered
2020-05-06
Start date
2019-03-11
Completion date
Unknown
Last updated
2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute respiratory distress syndrome (ARDS). Acute respiratory distress syndrome

Interventions

Intervention 1: Intervention group: the NAC group, which received routine medical care as well as 150 mg/kg day one through the intravenous injection and therapy will contentious as 50 mg/kg between 2

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Mechanical ventilation more than 48 hours PaO2/FiO2?ratio = 200 mmhg PEEP= 10 cm H2O Bilateral pulmonary infiltrates on the chest x ray

Exclusion criteria

Exclusion criteria: Patients who signed an informed consent form Patients with cardiac and pulmonary disease Pulmonary hypertension Viral and bacterial diseases including acquired immunodeficiency syndrome (AIDS),hepatitis, pulmonary tuberculosis History of chemotherapy The use of immunosuppressive drugs within the last three months Sensitivity to NAC History of transplantation within the last two years

Design outcomes

Primary

MeasureTime frame
Percent of respiratory index in questioner no 1. Timepoint: The NAC group, which received routine medical care as well as 150 mg/kg day one through the intravenous injection and therapy will contentious as 50 mg/kg between 2-4 days. Method of measurement: Mechanical ventilator apparatus.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMojtaba Ghorbi

Ahvaz University of Medical Sciences

ghorbi.m@ajums.ac.ir+98 41 3235 0348

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026