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The effect of oral Gabapentin and intravenous Dexamethasone on postoperative pain after hysterectomy

comparision of the effect of oral Gabapentin compare to intravenous Dexamethasone on postoperative pain after elective hysterectomy

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200421047160N2
Enrollment
93
Registered
2023-05-07
Start date
2023-04-04
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain intensity after hysterectomy surgery.

Interventions

Intervention 1: Intervention group: Half an hour before the start of surgery, 600 mg of oral gabapentin and intravenous placebo. Intervention 2: Intervention group: Half an hour before surgery, 8 mg o

Sponsors

Zanjan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
30 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patient consent to participate in the study ASA class 1 or 2 Candidate for non-emergency abdominal hysterectomy surgery Hysterectomy for non-malignant reasons Lack of sensitivity to Gabapentin and Corticosteroids No history of chronic pain and neurological diseases Not receiving any kind of pain medication in the last 24 hours Not having diabetes and Hypertention

Exclusion criteria

Exclusion criteria: Extending the duration of hysterectomy more than 3 hours Occurrence of any unusual complications during surgery Receiving pain medication during the operation

Design outcomes

Primary

MeasureTime frame
Pain score after hysterectomy. Timepoint: in hours 0 (recovery), 2, 6, 12, 24 after the operation. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
Determining the need for additional painkillers. Timepoint: in hours 0 (recovery), 1, 6, 12, and 24 hours after hysterectomy. Method of measurement: Patient request and registration in the medical record.;The rate of side effects (nausea and vomiting, confusion and drowsiness, palpitations). Timepoint: in hours 0 (recovery), 1, 6, 12, and 24 hours after hysterectomy. Method of measurement: registration in the medical record.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzadeh Hosseinkhani

Zanjan University of Medical Sciences

azihsnkhani@zums.ac.ir+98 24 3333 4261

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026