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The effect of oral dydrogesterone in supporting the luteal phase in patients undergoing in vitro fertilization treatment

Comparison of the effect of oral dydrogesterone with intramuscular progesterone in supporting the luteal phase in patients undergoing in vitro fertilization treatment, a non-inferiority clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200421047152N5
Enrollment
384
Registered
2023-11-25
Start date
2023-11-22
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility treated by in Vitro Fertilization. In vitro fertilization

Interventions

Intervention 1: Control group: the enrolled patients enter a cycle of 45 days. In this group, the LD pill starts from the third day of menstruation and continues, and on the 21st day of the cycle, Lau

Sponsors

Iranian academic center for education culture and research
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Women between 20-40 years old with a 5-day frozen embryo created by intracytoplasmic sperm injection (ICSI) Normal uterine cavity

Exclusion criteria

Exclusion criteria: Follicle stimulating hormone serum level above 12 FSH milliunits/ml History of endometriosis History of moderate to severe adenomyosis History of 3 or more previously failed embryo transfers Sex selection cycles Embryo donation cycles or surrogacy Hydrosalpinx Any type of uterine abnormalities (septum, etc.) Submucousal myoma Asherman syndrome

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy. Timepoint: 5 weeks after embryo transfer. Method of measurement: Trans vaginal ultrasound imaging.

Secondary

MeasureTime frame
Chemical pregnancy. Timepoint: Day 14 after embryo transfer. Method of measurement: Serum levels of beta human chorionic gonadotropin hormone (Beta HCG).;Ongoing pregnancy. Timepoint: 12 weeks after embryo transfer. Method of measurement: Trans abdominal ultrasound imaging.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomayeh Saleki

Iranian academic center for education culture and research

dr.somayeh.saleki2@gmail.com+98 21 23519

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026