Contrast-induced nephropathy. ????????
Conditions
Interventions
Intervention 1: Intervention group1: Sodium chloride + placebo N-acetylcysteine + real vitamin E. Intervention 2: Intervention group 2: Sodium chloride + real N-acetylcysteine + placebo vitamin E. Int
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with stable coronary disease at risk of acute myocardial infarction, who required coronary artery intervention (angiography) Patients with acute coronary syndrome, who required coronary artery intervention (angiography) Diabetic patients
Exclusion criteria
Exclusion criteria: Patients with hypersensitivity to contrast material Patients with cardiogenic shock Patients with pulmonary edema Patients with acute renal failure Patients with acute coronary syndrome who underwent angiography or angioplasty for the past 5 days Patients with recent injection of any contrast material (like radiologic interventions) Patients with history of dialysis Pregnant women Patients with acute myocardial infarction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 0.5 mg/dl increase in serum creatinine level or 25% compared to baseline was considered as contrast-induced nephropathy. Timepoint: Before and 48 hours after intervention. Method of measurement: Patients' serum test results. | — |
Secondary
| Measure | Time frame |
|---|---|
| The frequency of contrast-induced nephropathy. Timepoint: 48 hours after intervention. Method of measurement: Patients' serum test results. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMina Mirzai
Shahid Beheshti University of Medical Sciences
Outcome results
None listed