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Comparison of pethidine and bupivacaine in spinal anesthesia

Comparison of the effect of intrathecal injection of pethidine, pethidine-bupivacaine and bupivacaine on pain severity and hemodynamic parameters after elective cesarean section

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200413047056N2
Enrollment
90
Registered
2021-01-28
Start date
2021-01-31
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The rate of analgesia in cesarean section. Other complications of spinal and epidural anesthesia during labor and delivery

Interventions

Intervention 1: Intervention group 1: Healthy pregnant women 20 to 40 years old undergoing spinal anesthesia with pethidine. After prepping and draping, spinal anesthesia with 100mg of pethidine will

Sponsors

Birjand University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: ASA 1 and ASA 2 (patients with healthy or controlled mild disease) in the range of 20 to 40 years No drug and smoking addiction No history of hypertension, diabetes and uncontrolled comorbidities Elective cesarean section No chronic pain No mental disorder and hysteria

Exclusion criteria

Exclusion criteria: Emergency cesarean section Placental abruption Placental accreta Severe bleeding during surgery Drug and smoking addiction Uncontrolled comorbidities Take painkillers or antiemetics 24 hours before operation Skin infection at the site of lumbar injection History of bupivacaine or pethidine allergy Change ofanesthesia type during the operation Blood transfusion during the operation

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: Within 24 hours after the intervention. Method of measurement: Number of suppositories consumed.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaliheh Zangoue

Birjand University of Medical Sciences

Mzangoue@yahoo.com+98 56 3239 5000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026