COVID-19 disease.
Conditions
Interventions
Intervention 1: Intervention group: In addition to the common national protocol, this group will receive convalescent plasma of recovered individuals twice and 200 cc each time. Intervention 2: Interv
Sponsors
Birjand University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: RT-PCR Confirm the infection in the throat swab or sputum or lower respiratory tract samples. Sign the Informed Consent Form on a voluntary basis. Meet any of the following criteria for severe or critical ill conditions:Respiratory rate >=30/min; orRest SPO2<=90%; orPaO2/FiO2<=300mmHg; orRespiratory failure and needs mechanical ventilation; orMultiple organ failure and needs ICU monitoring
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lung involvement in X-ray and CT-scan, SPO2, LDH enzyme, viral load, acute phase protein, white blood cell count, ESR, length of hospital stay, duration of mechanical ventilation. Timepoint: from the start of the intervention for 12 days. Method of measurement: Blood and biochemical factors are measured using laboratory tests by an autoanalyzer. Pulmonary function indicators are measured by pulse oximetry and ABG. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMalihe Zangoue
Birjand University of Medical Sciences
Outcome results
None listed