Investigation of the effect of vitamin D treatment on asthenospermia in infertile patients with vitamin D insufficiency

Evaluation of the effect of vitamin D therapy on asthenospermia in infertile patients with vitamin D insufficiency

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200412047046N1

Enrollment

Registered

2020-04-25

Start date

2019-08-23

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthenospermia

Interventions

Intervention 1: Intervention Group: In addition to prescribing routine infertility treatments, prescribing Perl Vitamin D 5,000 units once a week for 8 weeks. Intervention 2: Control group: In the con

Eligibility

Sex/Gender

Male

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Asthenospermia Vitamin D insufficiency (20-30) Age 18-50

Exclusion criteria

Exclusion criteria: Normalization levels of vitamin D in the control group The presence of other organic diseases such as varicocele ? and genetic disorders and clinical syndrome

Design outcomes

Primary

Measure	Time frame
Asthenospermia (sperm motility factor in WHO criteria for motility less than a + b <30). Timepoint: perform spermograms at the beginning of the study and then six months later. Method of measurement: To perform a spermogram, should be performed at least 3 days and maximum 5 days after the last ejaculation . The patient's spermogram will be tested in a same reference center by an experienced operator.;Insufficiency of vitamin D (between 20-30). Timepoint: At the beginning of the study, three and a six months later. Method of measurement: In these patients, serum levels of vitamin D are measured through Anterior veins of the forearm from a blood sample.	—

Measure

Time frame

Asthenospermia (sperm motility factor in WHO criteria for motility less than a + b <30). Timepoint: perform spermograms at the beginning of the study and then six months later. Method of measurement: To perform a spermogram, should be performed at least 3 days and maximum 5 days after the last ejaculation . The patient's spermogram will be tested in a same reference center by an experienced operator.;Insufficiency of vitamin D (between 20-30). Timepoint: At the beginning of the study, three and a six months later. Method of measurement: In these patients, serum levels of vitamin D are measured through Anterior veins of the forearm from a blood sample.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Akhavanrezayat

Mashhad University of Medical Sciences

akhavanra@mums.ac.ir+98 51 3843 2256

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026