Effect of High Intensity Interval Training with Blood Flow Restriction on cardiovascular function of Cardiotoxic patients after Breast Cancer therapy

Effect of High Intensity Interval Training (HIIT) with Blood Flow Restriction (BFR) on cardiovascular function of Cardiotoxic patients after Breast Cancer therapy(pilot study)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200412047045N1

Enrollment

Registered

2020-08-21

Start date

2019-04-27

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Cardiotoxicity. Condition 2: Cardiac rehabilitation. Condition 3: Breast Cancer. Cardiomyopathy due to drug and external agent Therapeutic (nonsurgical) and rehabilitative cardiovascular devices associated with adverse incidents Malignant neoplasm of breast

Interventions

Intervention 1: Intervention group: High Intensity Interval Training. Intervention 2: Intervention group: Blood Flow Restriction. Intervention 3: Intervention group: High Intensity Interval Training w

Eligibility

Sex/Gender

Female

Age

No minimum to 65 Years

Inclusion criteria

Inclusion criteria: Breast Cancer patients Age < 65y Second phase of rehabilitation Without Cardiac diseaes before Cancer Treatment Treatment Drug: Anthracyclines 40 =Ejection Fraction= 50 Heart failure treatment: Beta blockers, ACEI Permission of Cardiologist Signature of consent letter

Exclusion criteria

Exclusion criteria: Conditions that cause the patient, not be able to perform the exercises(Fracture of limbs, pregnancy,…) Symptoms of severe heart failure Sign of recurrence of breast cancer (repeat chemotherapy)

Design outcomes

Primary

Measure	Time frame
Cardiovascular function. Timepoint: before intervention and after 12 weeks after intervention. Method of measurement: echocardiography.	—

Secondary

Measure	Time frame
New York Heart Association (NYHA) Functional Classification. Timepoint: before and after 12 weeks intervention. Method of measurement: the New York Heart Association (NYHA) Functional Classification. It places patients in one of four categories based on how much they are limited during physical activity.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Adimi

Islamic Azad University

sara_adimi@yahoo.com+98 21 2225 4405

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026