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Evaluation the effect of raltegravir, and raltegravir/interferon beta combination on covid 19 patients

Evaluation the effect of raltegravir, and raltegravir/interferon beta combination on covid 19 patients admitted in Peymanieh hospital of Jahrom in 2020

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200412047042N1
Enrollment
60
Registered
2020-06-11
Start date
2020-06-19
Completion date
Unknown
Last updated
2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19. COVID-19 disease

Interventions

Intervention 1: Intervention group 1:In addition to standard treatment (400 mg of hydroxychloroquine) in the amount of 400 mg of raltagravir twice a day for 10 days and will receive tablets. Intervent

Sponsors

Jahrom University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: confirmed diagnosis of COVID19 with RT-PCR hospitalized patients

Exclusion criteria

Exclusion criteria: Patients with severe dyspnea require mechanical ventilation or hospitalization in intensive care units and patients with treatment-resistant hypoxemia or those with severe underlying disease Pregnancy or breastfeeding Drug allergy Patient dissatisfaction

Design outcomes

Primary

MeasureTime frame
In this study, Sequential Organ Failure Assessment (SOFA) will be used to assess the severity of the disease. In this criterion, respiratory systems (PaO2 / Fio2 measurement), coagulation (platelet count), liver (bilirubin level), cardiovascular (hypotension), central nervous system (CNS) and kidney (creatinine level or urinary tract) Will be reviewed. Each parameter is graded on a 5-point Likert scale (score between zero and 4). The total score is between zero and 28. Higher scores indicate a worse patient condition. Timepoint: Before and after the intervention. Method of measurement: The data will be collected using the information in the patient's file.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Rahim Raoufi

Jahrom University of Medical Sciences

sarahim1513@gmail.com+98 71 5444 7760

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026