Effect of training, caloric restriction and vitamin D supplementation on body composition, lipid profile and plasma BDNF

Effect of four-week Water Aerobics training with and without caloric restriction and vitamin D supplementation on body composition, lipid profile and peripheral blood BDNF in adult females with overweight and obesity

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200411047036N1

Enrollment

Registered

2020-06-05

Start date

2018-09-06

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: overweight or obesity. Condition 2: Lipid profile (Triglycerides, High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), Total cholesterol. Condition 3: Peripheral blood Brain-Drived Neurotrophic Factor. Obesity due to excess calories Hyperlipidemia, unspecified Major depressive disorder, single episode

Interventions

Intervention 1: Intervention group: Water Aerobic Training, 12 sessions in 1 to 1.5 hours, three times a week, subjects will intake a Vitamin D placebo everyday without any calorie restriction. In tr

Eligibility

Sex/Gender

Female

Age

30 Years to 50 Years

Inclusion criteria

Inclusion criteria: women between 30 and 50 age group BMI= 30-35 kg/m2 women should be in pre-menopausal period women should have 9 to 11 menstural cycle in year

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Changes in serum Brain-Drived Neurotrophic Factor. Timepoint: Pre-test blood sampling of Brain-Drived Neurotrophic Factor performed on the eighth day of each woman's menstural cycle and Post-test performed on 48 hour after the latest training session (the sixth or eighth day of each woman's menstural cycle). Method of measurement: Serum Brain-Drived Neurotrophic Factor Concentration measured by the Competitive Sandwich Enzyme-Linked Immunoorbent Assay (ELISA) Test Using Crystal Day Biotech Kit made in China.;Waist circumference. Timepoint: Pre-test: the eighth day of each woman's menstural cycle Post-test: 48 hour after the latest training session (the sixth or eighth day of each woman's menstural cycle). Method of measurement: From the upper abdomen measured by a tape measure and after a normal exhalation.;Range of Body Mass Index. Timepoint: Pre-test: the eighth day of each woman's menstural cycle Post-test: 48 hour after the latest training session (the sixth or eighth day of each woman's menstural cycle). Method of measurement: By dividing the weight in kilograms by the height of the meter.;Fat percentage. Timepoint: Pre-test: the eighth day of each woman's menstural cycle Post-test: 48 hour after the latest training session (the sixth or eighth day of each woman's menstural cycle). Method of measurement: By caliper tool and using Jackson-Pollock 3Point method.;Body Fat Mass. Timepoint: Pre-test: the eighth day of each woman's menstural cycle Post-test: 48 hour after the latest training session (the sixth or eighth day of each woman's menstural cycle). Method of measurement: By measuring weight and multiplying the percentage of fat by the amount of weight.;Lean Body Mass. Timepoint: Pre-test: the eighth day of each woman's menstural cycle Post-test: 48 hour after the latest training session (the sixth or eighth day of each woman's menstural cycle). Method of measurement: By eliminating the amount of fat mass from the amount of weight.;Serum triglyceride levels.	—

Measure

Time frame

Changes in serum Brain-Drived Neurotrophic Factor. Timepoint: Pre-test blood sampling of Brain-Drived Neurotrophic Factor performed on the eighth day of each woman's menstural cycle and Post-test performed on 48 hour after the latest training session (the sixth or eighth day of each woman's menstural cycle). Method of measurement: Serum Brain-Drived Neurotrophic Factor Concentration measured by the Competitive Sandwich Enzyme-Linked Immunoorbent Assay (ELISA) Test Using Crystal Day Biotech Kit made in China.;Waist circumference. Timepoint: Pre-test: the eighth day of each woman's menstural cycle Post-test: 48 hour after the latest training session (the sixth or eighth day of each woman's menstural cycle). Method of measurement: From the upper abdomen measured by a tape measure and after a normal exhalation.;Range of Body Mass Index. Timepoint: Pre-test: the eighth day of each woman's menstural cycle Post-test: 48 hour after the latest training session (the sixth or eighth day of each woman's menstural cycle). Method of measurement: By dividing the weight in kilograms by the height of the meter.;Fat percentage. Timepoint: Pre-test: the eighth day of each woman's menstural cycle Post-test: 48 hour after the latest training session (the sixth or eighth day of each woman's menstural cycle). Method of measurement: By caliper tool and using Jackson-Pollock 3Point method.;Body Fat Mass. Timepoint: Pre-test: the eighth day of each woman's menstural cycle Post-test: 48 hour after the latest training session (the sixth or eighth day of each woman's menstural cycle). Method of measurement: By measuring weight and multiplying the percentage of fat by the amount of weight.;Lean Body Mass. Timepoint: Pre-test: the eighth day of each woman's menstural cycle Post-test: 48 hour after the latest training session (the sixth or eighth day of each woman's menstural cycle). Method of measurement: By eliminating the amount of fat mass from the amount of weight.;Serum triglyceride levels.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Afshar Jafari

Shahid Beheshti University

afshar.jafari@gmail.com+98 21 2243 1962

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026