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The effect of melatonin on the quality of sleep in COVID-19 patients

Evaluation of adding melatonin to routine treatment on outcomes and quality of sleep in COVID-19 patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200411047030N1
Enrollment
82
Registered
2020-04-17
Start date
2020-04-14
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19. Coronavirus infection, unspecified

Interventions

Intervention 1: Intervention group: COVID-19 patients receiving hydroxychloroquine (200 mg every 12 hours), azithromycin (500 mg daily) and melatonin tablets (3 mg every night before bedtime) for up t

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Consent to attend the study Clinical symptoms Lymphocyte count less than 1100 Positive CT scan or C-reactive protein

Exclusion criteria

Exclusion criteria: Epilepsy Taking warfarin and other anticoagulants and coagulation disorders Uncontrolled diabetes and high blood pressure

Design outcomes

Primary

MeasureTime frame
Stop the fever. Timepoint: It will be reviewed for 7 days from the study onset. Method of measurement: It is recorded by a thermometer.;Transfer to ICU. Timepoint: A maximum of 10 days of hospitalization will be checked. Method of measurement: Tracking hospitalized patients through questions and recording in questionnaires.;Mortality. Timepoint: A maximum of 10 days of hospitalization will be checked. Method of measurement: Tracking hospitalized patients through questions and recording in questionnaires.;Sleep quality. Timepoint: Days 1, 2, 3, and 7. Method of measurement: The Leeds Sleep Evaluation questionnaire will be used.

Secondary

MeasureTime frame
Lymphopenia status. Timepoint: It will be reviewed on the first day and day 7. Method of measurement: Cell counter device.;C-reactive protein status. Timepoint: It will be reviewed on the first day and day 7. Method of measurement: Serology test.;Peripheral capillary oxygen saturation (SPO2). Timepoint: It will be reviewed on the first day and day 7. Method of measurement: Pulse Oximeter.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Abbas Mousavi

Mazandaran University of Medical Sciences

mmm89099@gmail.com+98 11 3336 1700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026