Cardiovascular disorders. Cardiovascular disease, unspecified
Conditions
Interventions
Intervention 1: Intervention group: This group has a two-meal diet, which means that only two meals will be served in 24 hours. This diet will last for 16 weeks (4 months). The first meal will be in t
Sponsors
Research Deputy of The Qom University of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to No maximum
Inclusion criteria
Inclusion criteria: person's desire to participate in the trial Having the physical ability to complete the trial No prohibition to comply with the diet Having no special diet beforehand Lack of acute phase of inflammatory diseases and the gastrointestinal tract disorders Having the body mass index above 24.9 No history of ulcers and inflammation of the upper gastrointestinal tract, as well as a history of gastrointestinal bleeding and inflammatory diseases of the gastrointestinal tract, including Crohn's disease and ulcerative colitis.
Exclusion criteria
Exclusion criteria: Lack of desire to participate in the trial Lack of physical ability to complete the trial Have been banned on trial diet Having special diet Acute phase of inflammatory diseases and the gastrointestinal tract disorders History of ulcers and inflammation of the upper gastrointestinal tract, as well as a history of gastrointestinal bleeding and inflammatory diseases of the gastrointestinal tract, including Crohn's disease and ulcerative colitis. Advanced diabetes mellitus or insulin-mediated diabetes mellitus due to the potential for damage due to reactive hypoglycemia History of previous recurrent hypoglycemia Having severe debilitating disorders at the same time Consumption high-dose corticosteroids, chemotherapy drugs, and cytotoxic drugs Having untreated glandular diseases, especially thyroid and adrenal disorders Body mass index less than 25
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: Beginning and end of the study. Method of measurement: Scales.;Blood pressure. Timepoint: Beginning and end of the study. Method of measurement: Sphygmomanometer.;Functional status of systole and diastole of left ventricular. Timepoint: Beginning and end of the study. Method of measurement: Transthoracic echocardiography.;Body fat percentage. Timepoint: Beginning and end of the study. Method of measurement: Bioelectrical impedance device.;Carotid intimal thickness. Timepoint: Beginning and end of the study. Method of measurement: Carotid sonography.;CRP serum level. Timepoint: Beginning and end of the study. Method of measurement: CRP kit quantitatively made by Pishtazteb company.;Lipid profile. Timepoint: Beginning and end of the study. Method of measurement: Lipid assay kit.;The level of malonyl dialdehyde. Timepoint: Beginning and end of the study. Method of measurement: Standard kit of malonyl dialdehyde.;The level of BAX. Timepoint: Beginning and end of the study. Method of measurement: Standard kit of BAX.;The level of Bcl2. Timepoint: Beginning and end of the study. Method of measurement: Standard kit of Bcl2.;Fasting Blood Sugar Test. Timepoint: Beginning and end of the study. Method of measurement: glucometer.;HbA1c. Timepoint: Beginning and end of the study. Method of measurement: affinity chromatography methods.;Uric acid test. Timepoint: Beginning and end of the study. Method of measurement: Uric acid laboratory test kit.;Hip circumference size. Timepoint: Beginning and end of the study. Method of measurement: sewing meter.;Waist size. Timepoint: Beginning and end of the study. Method of measurement: sewing meter.;Serum insulin levels. Timepoint: Beginning and end of the study. Method of measurement: Laboratory Insulin Assay Kit.;Insulin resistance. Timepoint: Beginning and end of the study. Method of measurement: Oral glucose tolerance test.;Serum glutathione. Timepoint: Beginning and end of the study. Method of measurement: Glutathio | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHossein Sheibani
Shahroud University of Medical Sciences
Outcome results
None listed