Skip to content

Effect of COVID 19 survivors plasma in COVID 19 patients with ARDS

The effect of plasma administration of COVID-19 survivors in patients with acute respiratory distress syndrome due to COVID-19

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200409047007N1
Enrollment
64
Registered
2020-04-12
Start date
2020-04-13
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19 Disease. COVID-19 Disease

Interventions

Intervention 1: Intervention group: In the intervention group, patients, in addition to the current standard treatments, also receive 600 cc survivor's plasma. For the preparation of fresh plasma prod

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Po2 / FIO2 ratio less than 300 despite receiving standard treatment The patient should be between 18 and 75 years old Normal IgA level Less than a week has passed since the patient entered the ICU

Exclusion criteria

Exclusion criteria: Uncontrolled HTN Advanced heart failure Systolic blood pressure less than 90 mm Hg COPD The patient is intubated Chronic renal failure with GFR less than 30 Advanced hepatic failure

Design outcomes

Primary

MeasureTime frame
Mortality rate in 4 weeks from the time of entry into the study. Timepoint: The first month of entering the study. Method of measurement: Continuous clinical evaluation.

Secondary

MeasureTime frame
The length of hospital stay in the ICU from the time of entering the study. Timepoint: Daily evaluation. Method of measurement: Clinical evaluation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohsen Seddigh Shamsi

Mashhad University of Medical Sciences

seddighshamsim@mums.ac.ir+98 51 3859 8818

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026