Evaluation of the effect of hyaluronic acid in the prevention of Asherman's syndrome.

Investigation of the effect of intrauterine hyaluronic acid on the prevention of Asherman's syndrome in cases of endometrial injury in patients with septal resection surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200408046993N1

Enrollment

Registered

2020-04-16

Start date

2019-11-04

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asherman syndrome. Intrauterine synechiae

Interventions

Intervention 1: Intervention group: Injection of 1 cc of hyaluronic acid gel into the uterine cavity. Intervention 2: Control group: Injection of 1 cc of normal saline solution as a placebo into the u

Eligibility

Sex/Gender

Female

Age

15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Candidates for uterine septal resin surgery who have suffered endometrial damage during surgery. Age 15-45 years

Exclusion criteria

Exclusion criteria: BMI > 35 kg/m2 Menopause Pregnancy Cervical cancer Coagulation disorder Severe pelvic infections People who do not willing to cooperate after explaining the work.

Design outcomes

Primary

Measure	Time frame
Intrauterine adhesions. Timepoint: Two times, before and 2 months after intervention. Method of measurement: Hysteroscopy and American Society of Reproductive Medicine scoring system.;Volume of menstrual bleeding. Timepoint: Two times, before and 2 months after intervention. Method of measurement: Questionnaire.;Number of menstrual days. Timepoint: Two times, before and 2 months after intervention. Method of measurement: Questionnaire.	—

Measure

Time frame

Intrauterine adhesions. Timepoint: Two times, before and 2 months after intervention. Method of measurement: Hysteroscopy and American Society of Reproductive Medicine scoring system.;Volume of menstrual bleeding. Timepoint: Two times, before and 2 months after intervention. Method of measurement: Questionnaire.;Number of menstrual days. Timepoint: Two times, before and 2 months after intervention. Method of measurement: Questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtiyeh Javaheri

Yazd University of Medical Sciences

a.javaheri@ssu.ac.ir+98 35 3822 4000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026