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A comparison of Dabigatran, Enoxaparin and Rivaroxaban for venous thromboembolism prophylaxis

A comparison of Dabigatran, Enoxaparin and Rivaroxaban for venous thromboembolism prophylaxis in cancer patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200407046984N1
Enrollment
57
Registered
2020-07-06
Start date
2020-02-20
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Deep vein thromboembolism. Condition 2: Malignant neoplasm of lower respiratory tract. Acute embolism and thrombosis of deep veins of lower extremity Malignant neoplasm of lower respiratory tract, part unspecified

Interventions

Intervention 1: Control group: There are 35 patients. In this group, subcutaneous injections are given daily for 3 months to prevent DVT Enoxaparin at a dose of 40 mg. Intervention 2: Intervention gro

Sponsors

Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Cancer patients referred to Kosar Hospital in Semnan (all metastatic patients with either progressive symptoms or in the phase of slowing down the disease)

Exclusion criteria

Exclusion criteria: High blood pressure (180/120 or more) Moderate or severe hepatic insufficiency Glomerular filtration rate (GFR) less than 30ml / min Severe bleeding (requiring hospitalization) Blood and hemorrhagic diseases include: hemophilia, Von Willebrand factor deficiency, problems of factors 2, 5, 7,10 and 12, types of Anemia, blood transfusions, Thrombocytopenia, Bernard-Soulier syndrome, Glanzmann, plaque pool storage deficiency syndrome, Vitamin K deficiency, Dysfibrinogenemia, Immune thrombocytopenia purpura (ITP), Acute lymphoblastic leukemia (ALL), Bleeding diathesis

Design outcomes

Primary

MeasureTime frame
Thromboembolism. Timepoint: After seeing the initial symptoms taught to the patient himself. Method of measurement: Doppler ultrasound.;Bleeding. Timepoint: After seeing the initial symptoms taught to the patient himself. Method of measurement: PTT? Activated PTT? BT.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPouya Youseflee

Semnan University of Medical Sciences

Pouyalee@gmail.com+98 51 3841 2555

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026