diabetic macular edema. Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy with macular edema
Conditions
Interventions
Intervention 1: Control group: Patients with insufficient/ deficient leveLs of vitamin D and diabetic macular edema
Intervention: IVB. Intervention 2: Intervention group: Patients with insufficient/deficient levels of vitamin D and diabetic macular edema
Intervention: IVB+Vitamin D oral supplementation.
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with diabetes mellitus type 2 and diabetic macular edema Central macular thickness equal and greater than 300 micron Corrected distance visual acuity of greater than 0.1 LogMAR
Exclusion criteria
Exclusion criteria: History of any intraocular surgery (except uncomplicated cataract surgery which at least 6 months are passed) History of intravitreal injection of bevacizumab, other anti-VEGFs and steroid within 3 past months Epiretinal membrane or vitreomacular traction History of retinal vascular accidents History of uveitis Pregnant or breastfeeding women Using vitamin supplementation Not taking vitamin D supplementation based on the study protocol during follow up period Patients with severe vitamin D deficiency ( 3 mg/dl
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in central macular thickness in microns. Timepoint: Before treatment, 1 month, 3 months and 6 months after third baseline IVB. Method of measurement: Optical coherence tomography device. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSepehr Roozdar
Shahid Beheshti University of Medical Sciences
Outcome results
None listed