Covid 19 induced acute respiratory distress syndrome. Covid 19 virus identified
Conditions
Interventions
Intervention 1: Intervention group: Patients who underwent plasmapheresis for 3 days in addition to routine treatment (Includes ventilation supportive care, serum therapy, treatment with heparin or en
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to No maximum
Inclusion criteria
Inclusion criteria: The patient must be definitive case of Covid-19 based on positive PCR test. The patient must have clinical and paraclinical criteria for acute respiratory distress syndrome (ARDS) The patient age must be over 15 years There must be the informed consent of the patient or his/her legal guardian
Exclusion criteria
Exclusion criteria: The patient has unstable hemodynamics The patient has a history of previous acute cardiac infarction in the last 3 months The patient has a history of allergies to blood products
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Death. Timepoint: first 30 days of hospital admission. Method of measurement: examination of vital signs. | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease severity. Timepoint: 1st, 3rd and 7th day after ICU admission. Method of measurement: Use of SAPS3 and SOFA scoring systems.;ICU ward stay. Timepoint: Day 30 and 60 from hospital admission. Method of measurement: Patient visit.;Mechanical ventilation duration. Timepoint: All days of ICU admission. Method of measurement: Daily visit.;Changes in CRP and Ferritin inflammatory markers. Timepoint: Days 0, 3 and 7 after ICU admission. Method of measurement: Serum levels of CRP and ferritin tests. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Moeini nodeh
Mashhad University of Medical Sciences
Outcome results
None listed