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Vitamin A and COVID-19

The effect of supplementation with vitamin A on improvement of symptoms of acute respiratory syndrome in patients with COVID-19: A randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200405046951N1
Enrollment
120
Registered
2020-06-11
Start date
2020-05-21
Completion date
Unknown
Last updated
2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid-19.

Interventions

Intervention 1: Intervention group: receiving Vitamin 50000 IU through injection. Intervention 2: Control group: Routine care.

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Being at the age of 18-80 years old The same treatment protocol Desire to participate in project

Exclusion criteria

Exclusion criteria: Severe liver and biliary disease and known pancreatitis History of vitamin A supplementation last month Pregnancy Lactation

Design outcomes

Primary

MeasureTime frame
Weaning time of ventilator. Timepoint: Before and after of intervention. Method of measurement: time assessment.—

Secondary

MeasureTime frame
Rapid shallow breathing index (RSBI). Timepoint: before and after intervention. Method of measurement: ventilator.;Pao2/Fio2 ratio. Timepoint: before and after intervention. Method of measurement: ventilator.;Fraction of inspired oxygen (FiO2). Timepoint: before and after intervention. Method of measurement: ventilator.;Oxygen saturation. Timepoint: before and after intervention. Method of measurement: ventilator.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzadeh Mottaghi

Iran University of Medical Sciences

mottaghi.azadeh@gmail.com+98 21 8603 6080

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026