COVID-19 disease. COVID-19
Conditions
Interventions
Intervention 1: Intervention group: Patients hospitalized with COVID-19 disease who in addition to their standard treatment will be received 250mg/day Methylprednisolone? for 3 days. Intervention 2: C
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: COVID-19 patient confirmed by positive PCR ?test for SARS-CoV-2 or abnormal CT scan finding (bilateral, sub pleural, peripheral ground glass ?opacities), Blood oxygen saturation 30 breaths/minute, before connecting to ventilator and intubation.?
Exclusion criteria
Exclusion criteria: Patients with uncontrolled type I diabetes, blood pressure, positive pro-calcitonin, active infection, and ?taking any immune-suppressor agents, will exclude from the study.?
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Radiographic features Findings. Timepoint: Before and at discharge time only in patients agreed ?to give informed consent. Method of measurement: CT scan.;Mortality rate. Timepoint: Before and after. Method of measurement: Observation.;O2 saturation. Timepoint: Before and after ( by 3 days of treatment and at discharge). Method of measurement: Pulse Oximeter.;Need an oxygen therapy ?. Timepoint: Before and after (at day 3 and discharge time). Method of measurement: clinical. | — |
Secondary
| Measure | Time frame |
|---|---|
| Laboratory tests. Timepoint: Before and after (at day 3, and discharge time). Method of measurement: Para-clinical. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAbdorahman Rostamian
Tehran University of Medical Sciences
Outcome results
None listed