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Evaluation the effect of licorice for treatment of coronavirus

Evaluation the effect of aqueous extract of licorice on coronavirus outpatients: A randomized, double-blind, placebo-controlled clinical trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200404046933N1
Enrollment
40
Registered
2020-04-12
Start date
2020-04-20
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid-19. Covid-19 disease

Interventions

Intervention 1: Intervention group: In addition to the standard treatment regimen for covid-19, capsules which have aqueous licorice extract containing 80 mg of the active ingredient glycyrrhizin w

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients diagnosed for coronavirus according to clinic such as fever, cough and mylagia Patients diagnosed for coronavirus according to paraclinic such as lymphopenia and increase of CRP Patients in the range of 18-65 years old

Exclusion criteria

Exclusion criteria: Sensitivity to licorice and it derivatives Patients with hepato, renal or respiratory disorders Patients who take cytotoxic or corticosteroid drugs Nursing or pregnant women

Design outcomes

Primary

MeasureTime frame
Time interval until clinical symptoms improve. Timepoint: 3 days, 1 week and 2 weeks after treatment. Method of measurement: Time of recovery.;Lymphopenia. Timepoint: 3 days, 1 week and 2 weeks after treatment. Method of measurement: Cell counter device.;CRP level. Timepoint: 3 days, 1 week and 2 weeks after treatment. Method of measurement: CRP kit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGholamreza Karimi

Mashhad University of Medical Sciences

karimig@mums.ac.ir+98 51 3180 1191

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026