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Comparison of the effect of Lidocaine and a mixture of Lidocaine and Granisetron on axillary block

Comparison of duration of analgesia in Axillary block with Lidocaine and a mixture of Lidocaine and Granistron in patients requiring lower elbow surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200402046916N1
Enrollment
90
Registered
2020-11-06
Start date
2018-12-24
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients require lower elbow surgery.

Interventions

Intervention 1: Intervention group: 5 mg / kg Lidocaine 0.5% is diluted with 0.9% normal saline to 40 cc. After impregnating the syringe with epinephrine, 40 cc of Lidocaine solution and 2 mg of Grani

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 58 Years

Inclusion criteria

Inclusion criteria: Patients who are candidates for elbow and below elbow surgery Patients between the ages of 18-58 years Patients whose level of consciousness is above 14 according to the Glasgow standard

Exclusion criteria

Exclusion criteria: Patients who are allergic to Lidocaine and granisterone Patients who take drugs that interact with Lidocaine and Granistron Patients who have a lesion or infection at the injection site Patients with a history of coagulopathy

Design outcomes

Primary

MeasureTime frame
The onset of sensory block. Timepoint: The onset of sensory block will be measured at 6 and 12 hours after the intervention and also at the time of the first need for analgesia. Method of measurement: By examining and the PIN PRINK test.;The onset of motor block. Timepoint: The onset of motor block will be measured at 6 and 12 hours after the intervention and also at the time of the first need for analgesia. Method of measurement: Examination and the patient's ability in adduction flexion and finger extension.;The duration of sensory block. Timepoint: The duration of sensory block will be measured at 6 and 12 hours after the intervention and also at the time of the first need for analgesia. Method of measurement: By examination and PIN PRINK test.;The duration of motor block. Timepoint: The duration of motor block will be measured at 6 and 12 hours after the intervention and also at the time of the first need for analgesia. Method of measurement: Examination and the patient's ability in adduction flexion and finger extension.;Pain score. Timepoint: The pain score will be measured at 6 and 12 hours after the intervention and also at the time of the first need for analgesia. Method of measurement: By interviewing and the Numeric Rating Scale system.

Secondary

MeasureTime frame
Blood pressure. Timepoint: Before the intervention, every 10 minutes during the intervention and 2 and 6 hours after. Method of measurement: Measuring patient's blood pressure by monitoring and a Sphygmomanometer.;Heart rate. Timepoint: Before the intervention, every 10 minutes during the intervention and 2 and 6 hours after. Method of measurement: Measuring the patient's heart rate by monitoring and pulse counting.;Respiration. Timepoint: Before the intervention, every 10 minutes during the intervention and 2 and 6 hours after. Method of measurement: Measuring the patient's respiration by monitoring, using the number of breaths per minute.;Time for taking analgesia. Timepoint: 6 and 12 hours after the intervention. Method of measurement: Based on pain scores, analgesic is injected in a pain score of 6 or more.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPardis Vakili

Ahvaz University of Medical Sciences

vakilipardis@yahoo.com+98 61 3222 2922

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026