Condition 1: COVID-19. Condition 2: COVID-19. virus identified virus not identified
Conditions
Interventions
Intervention 1: Intervention group: Ivermectin (Alborz-Daru) 12 mg/day (Four 3 mg Tablets) orally for 2 days + standard care for 10 days or hospital discharge (whichever comes first). Intervention 2:
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: All Covid-19 patients admitted to the coronavirus ward of Razi Hospital in Rasht for period of April to July 2021 Age greater than or equal to 18 years Patients admitted with the following criteria: fever (oral temperature greater than 37.2 ° C), dry cough, severe tiredness or dyspnea At least one of the following criteria : positive PCR OR lung involvement on chest X-ray / CT scan
Exclusion criteria
Exclusion criteria: Lack of informed consent Lack of patient cooperation Having pulmonary embolism or intravascular thrombosis Any major drug interaction between routine patient's drugs with any of the study drugs Pregnancy and lactation Simultaneous presence in other research study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time required to improve clinical symptoms within 10 days of treatment start. Timepoint: Daily from the first day of intervention. Method of measurement: Physical examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Body temperature. Timepoint: Daily from the first day of intervention. Method of measurement: Thermometer.;Heart rate. Timepoint: Daily from the first day of intervention. Method of measurement: Pulse oxymeter.;Blood pressure. Timepoint: Daily from the first day of intervention. Method of measurement: Barometer.;Respiration rate. Timepoint: Daily from the first day of intervention. Method of measurement: Count.;SPO2. Timepoint: Daily from the first day of intervention. Method of measurement: Pulse-oxy mete.;Duration of hospitalization. Timepoint: Daily from the first day of intervention. Method of measurement: Record in the patient file.;Mortality. Timepoint: Daily from the first day of intervention. Method of measurement: Record in the patient file.;Creatine phosphokinase. Timepoint: Before intervention, Day 5 and Day 10. Method of measurement: International Federation of Clinical Chemistry (IFCC).;C reactive protein. Timepoint: Before intervention, Day 5 and Day 10. Method of measurement: Turbidometry.;Erythrocyte sedimentation rate. Timepoint: Before intervention, Day 5 and Day 10. Method of measurement: Westergren method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNematollah Ahangar
Rasht University of Medical Sciences
Outcome results
None listed