The effect of vancomycin in preventing surgical wound infection.

Evaluation the Efficacy and safety of topical vancomycin paste in preventing sternal wound infection in patients with cardiac surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200328046886N7

Enrollment

240

Registered

2025-03-30

Start date

2024-12-21

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sternal wound infection. Staphylococcus aureus as the cause of diseases classified elsewhere

Interventions

Intervention 1: Intervention group In these patients, after median sternotomy, a paste consisting of 3 grams of vancomycin powder (dana, Tabriz) diluted in 2 ml of normal saline was prepared at the su

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1-Completion of the consent form by the patient or his/her guardian. 2. over 18 years old 3- Patient is a candidate for cardiac surgery including (CABG, valve replacement or combination of CABG and valve replacement)

Exclusion criteria

Exclusion criteria: Pregnancy active infection ( positive culture sample) Organ transplant patients Patients with a history of vancomycin sensitivity

Design outcomes

Primary

Measure	Time frame
Number of sternum wound infections. Timepoint: 2 weeks and 2 months after surgery. Method of measurement: By designed investigator checklist.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamideh Abbaspour Kasgari

Mazandaran University of Medical Sciences

dr.abbaspour1@yahoo.com+98 11 4203 1035

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026