Effect of exercise on some serum factors in children with type 1 diabetes

Comparison of the effect of resistance and aerobic training on the expression of microRNA-192 and serum levels of GLP-1, GABA, Pentraxin3 and HbA1c in children with type 1 diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200326046861N2

Enrollment

Registered

2022-05-14

Start date

2022-07-06

Completion date

Unknown

Last updated

2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 1 diabetes. Diabetes mellitus due to underlying condition

Interventions

Intervention 1: Intervention group 1: It consists of a group of 15 members with a resistance exercise protocol (exercises at home, with minimal exercise equipment and involving different muscle groups

Eligibility

Sex/Gender

All

Age

No minimum to 18 Years

Inclusion criteria

Inclusion criteria: Type 1 diabetes at least one year after diagnosis

Exclusion criteria

Exclusion criteria: Diseases that prevent people from participating in exercising activities.

Design outcomes

Primary

Measure	Time frame
Investigation of changes in microRNA-192. Timepoint: Before and after the eight-week period of exercise. Method of measurement: PCR.;Evaluation of changes in GLP-1 protein in serum. Timepoint: Before and after the eight-week period of exercise. Method of measurement: ELISA.;Evaluation of changes in GABA protein in serum. Timepoint: Before and after the eight-week period of exercise. Method of measurement: ELISA.;Evaluation of changes in Pentraxin3 protein in serum. Timepoint: Before and after the eight-week period of exercise. Method of measurement: ELISA.	—

Measure

Time frame

Investigation of changes in microRNA-192. Timepoint: Before and after the eight-week period of exercise. Method of measurement: PCR.;Evaluation of changes in GLP-1 protein in serum. Timepoint: Before and after the eight-week period of exercise. Method of measurement: ELISA.;Evaluation of changes in GABA protein in serum. Timepoint: Before and after the eight-week period of exercise. Method of measurement: ELISA.;Evaluation of changes in Pentraxin3 protein in serum. Timepoint: Before and after the eight-week period of exercise. Method of measurement: ELISA.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Nazari

University of Isfahan

m.nazari1320@yahoo.com+98-313-7932003-7

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026