Colistin Resistant Klebsiella Pneumoniae. Pneumonia due to Klebsiella pneumoniae
Conditions
Interventions
Intervention 1: Intervention group: Doxycycline + Standard Treatment + Colistin: the medication regimen of this group will be doxycycline 100 capsules twice a day along with Colistin 2.5-5 mg/kg BD an
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Positive culture response to Klebsiella Pneumoniae and its resistance to Colistin Age 18 or above Insensitivity/interference of Doxycycline with the patient's current treatment.
Exclusion criteria
Exclusion criteria: Negative culture response to Klebsiella and subsidence of clinical symptoms Causing severe side effects in the patient during treatment Lack of consent of the patient or their companions to participate or continue the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluating patient's clinical symptoms, especially fever. Timepoint: daily. Method of measurement: vital signs monitor. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mortality rate. Timepoint: daily. Method of measurement: Loss of vital signs and death of the patient.;Investigating the possibility of recurrent infections. Timepoint: one week after the intervention. Method of measurement: blood culture. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShaghayegh Abaft
Islamic Azad University
Outcome results
None listed