topical simvastatin in diabetic foot ulcer

Evaluating the effect of topical simvastatin 2% ointment on the healing of diabetic foot ulcer in comparison with the routine treatment

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200325046854N3

Enrollment

Registered

2023-10-28

Start date

2023-11-16

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetic foot ulcer. Diabetes mellitus due to underlying condition with foot ulcer

Interventions

Intervention 1: Intervention group:Patients in Rasoul Akram Hospital, diagnosed with Wagner grade 2 diabetic foot ulcer, will be treated with simvastatin 2% ointment. Ointment will be administered twi

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: A patient with Wagner grade 2 diabetic foot ulcer Not using topical antibiotics for the patient A patient with no symptoms of septicemia, septic shock or organ dysfunction syndrome The age of the patient should not be less than 18 years and not more than 70 years.

Exclusion criteria

Exclusion criteria: Receive other topical treatments for diabetic foot ulcers

Design outcomes

Primary

Measure	Time frame
Grading the type and severity of the wound. Timepoint: Day 0, 7 and 14. Method of measurement: The size, amount of discharge and smell of the wound.;Evaluating the apparent progress of wound healing. Timepoint: Day 0, 7 and 14. Method of measurement: Imaging.	—

Secondary

Measure	Time frame
Possible side effects. Timepoint: Day 0, 7 and 14. Method of measurement: Descriptive.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Jamali

Islamic Azad University

fateme_jamali77@yahoo.com+98 21 2264 0051

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026