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Effectiveness of vitamin C on the improvement process of patients with COVID-19

Evaluation of the effectiveness of vitamin compared to routine medication treatment on the improvement process of patients with COVID-19

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200324046850N5
Enrollment
400
Registered
2020-04-04
Start date
2020-10-17
Completion date
Unknown
Last updated
2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid-19. Covid-19

Interventions

Intervention 1: Control group: Standard Protocol Drugs + placebo (in terms of appearance and color similar to vitamin C) every 12 hours for 5 days. Intervention 2: Intervention group: Standard Protoc

Sponsors

Abadan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: COVID-19 patients that have positive PCR test of nasopharyngeal sample or have positive CT Scan

Exclusion criteria

Exclusion criteria: Pregnant or breast feeding women Patients with kidney stone Patients with diabetes Patients under 18 years of age Chronic renal failure Patient with urinary tract infection

Design outcomes

Primary

MeasureTime frame
Recovery within 10 days of starting the drug. Recovery means: (no fever, no shortness of breath, no cough or improved, no fatigue or improved) for 24 hours. Timepoint: Daily. Method of measurement: Clinical observation and examination.

Secondary

MeasureTime frame
The change of inflammatory markers. Timepoint: Admission and discharge day. Method of measurement: C-reactive protein, neutrophil-lymphocyte ratio.;Rate of survival. Timepoint: Daily. Method of measurement: census report.;Days admitted in hospital. Timepoint: Daily since hospitalization time. Method of measurement: Based on patient's file.;Days intubated/under ventilator. Timepoint: Daily. Method of measurement: observation.;Days admitted in ICU. Timepoint: Daily. Method of measurement: Based on patient's file.;Time to clinical improvement (TTIC) of NEWS2 (National Early Warning Score 2) of 0 maintained for 24 hours. Timepoint: Day of admission, fifth and discharge. Method of measurement: NEWS2 (National Early Warning Score 2) questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Mobarak

Abadan University of Medical Sciences

S.mobarak@abadanums.ac.ir+98 61 5326 7800

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 24, 2026