Comparative study of the effect of fluoxetine and gabapentin in diabetic foot patients

Comparison of Fluoxetine and Gabapentin Effect on foot pain in Diabetic Foot Patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200324046850N4

Enrollment

100

Registered

2020-03-30

Start date

2020-05-20

Completion date

Unknown

Last updated

2020-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic foot ulcer. Non-pressure chronic ulcer of thigh

Interventions

Intervention 1: Intervention group: fluoxetine 20 mg daily. Intervention 2: Intervention group: Gabapentin 300 mg once daily.

Eligibility

Sex/Gender

All

Age

15 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria are: at least one year past diagnosis of diabetes, symptoms of neuropathy and tendency to participate in the study, as well as diabetic foot patients with grade 1 (superficial ulcer) and grade 2 (deep tendon ulcer or articular capsule) will be included in the study

Exclusion criteria

Exclusion criteria: Cases such as patients with concomitant cardiovascular disease, noncompliance with medication and trials, and diabetic foot patients with grade 3 or more ulcer are excluded.

Design outcomes

Primary

Measure	Time frame
Severity of pain. Timepoint: On the first days, 15 and 30 examinations. Method of measurement: Pain assessment is done on the first, 15th, and 30th days after intervention based on the VAS index, both verbally and visually.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Mobarak

Abadan University of Medical Sciences

S.mobarak@abadanums.ac.ir+98 61 5326 7800

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026