Infection caused by COVID-19. COVID-19, virus identified’ is assigned to a disease diagnosis of COVID-19 confirmed by laboratory testing
Conditions
Interventions
Intervention group: Patients who suffer from sever (ARDS patients who are not admitted in ICU) or very severe (ARDS or related symptoms and signs who are admitted in ICU) complications of COVID-19, re
Sponsors
Tehran University of Medical Sciences
University of social welfare and rehabilitation sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age between 18-65 years Known case of Covid-19 by relative signs, symptoms, Lab. radiology and CT scan Data Existence of Severe symptoms and signs of the disease (infection by COVID-19) Not taking any immunstimulators during last three months. Completed consent form by the patients or guardians
Exclusion criteria
Exclusion criteria: Recent drug abuse or alcohol consumption. Taking growth hormone, testosterone or anabolic steroids during last 30 days. Long term use of immunosuppressives. Chemotherapy, treatment by interferon or radiotherapy during last 3 weeks• Pregnancy or breast feeding Positive symptoms for common cold or positive PCR result for influenza but not confirmed COVID-19
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of admission days. Timepoint: every day. Method of measurement: Number of days.;The mortality rate in COVID-19 patients. Timepoint: Everyday. Method of measurement: Number of death.;Assessment of potential side effects. Timepoint: Every day. Method of measurement: Inspection for potential side effects. | — |
Secondary
| Measure | Time frame |
|---|---|
| Symptoms including coughing, fever, respiratory distress, etc. Timepoint: Every day. Method of measurement: By inspection and assessment of patients.;It is defined by the test results for: Blood gases, CBC, WBC, lymphocyte and Platelet counts; Coagulation testing; measurement of electrolytes; liver and renal function tests; CRP, LDH, Creatine kinase. Timepoint: At least every three days. Method of measurement: Measurements of Blood gases and Blood indices.;Performing radiologic and CT scan. Timepoint: At lease at the admission and discharge of patients. Method of measurement: Using radiology and CT scan equipments. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamidreza Khorram Khorshid
University of social welfare and rehabilitation sciences
Outcome results
None listed