The participant of this study are workers who exposed to harmful agent include cement dust, silica, noise in cement plant.
Conditions
Interventions
Intervention 1: Intervention group: This group will 40 participants that use vitamin E and vitamin C, The does of them by arrangement are 400 IU and 500mg. They will use these vitamins for tow month
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Have at least 5 years job experience sign the written informed consent
Exclusion criteria
Exclusion criteria: Workers have underlying disease including diabetes, heart disease, kidney disease,gastrointestinal discomfort, and hypertension Using particular drug or vitamins that effect on our intervention
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Malondialdehyde. Timepoint: malondialdehyde measurement will be performed One day befor the intervention, And one day after the intervention. Method of measurement: Malondialdehyde will measure based on its reaction with thiobarbituric acid reactive substances and will determine by using fluorimetry.;Total antioxidant capacity. Timepoint: Total antioxidant capacity measurement will be performed One day befor the intervention, And one day after the intervention. Method of measurement: Total antioxidant capacity will be measured by ferric reducing ability in plasma method.;Superoxide dismutase. Timepoint: Superoxide dismutase measurement will be performed One day befor the intervention, And one day after the intervention. Method of measurement: Activity of superoxide dismutase will measure by superoxide dismutase kit.;Catalase. Timepoint: Catalase measurement will be performed One day befor the intervention, And one day after the intervention. Method of measurement: Catalase enzyme will determine by catalase kit.;Alkaline phosphatase. Timepoint: Alkaline phosphatasemeasurement will be performed One day befor the intervention, And one day after the intervention. Method of measurement: Alkaline phosphatase will be measured by using standard kit and auto analyzer system.;Alanine transaminase. Timepoint: Alanine transaminasemeasurement will be performed One day befor the intervention, And one day after the intervention. Method of measurement: alanine transaminase will be measured by using standard kit and auto analyzer system.;Aspartate transaminase. Timepoint: Aspartate transaminasemeasurement will be performed One day befor the intervention, And one day after the intervention. Method of measurement: Aspartate transaminase will be measured by using standard kit and auto analyzer system.;High density lipid. Timepoint: High density lipid measurement will be performed One day befor the intervention, And one day after the intervention. Method of measurement: High density lip | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFaeze Darabi
Shiraz University of Medical Sciences
Outcome results
None listed